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Antimicrobial Screening Facility

Antimicrobial Screening Facility

Robot

High-throughput screening: MIC hit detection, synergy and more...

In collaboration with WISB, Warwick Antimicrobial Screening Facility are now offering automation and high-throughput services

  • High-throughput MIC hit detection, synergy checkerboard screening and the potential to automate your bespoke application.
  • Our Tecan Freedom EVO liquid handling platform enables us to provide a faster and more affordable antimicrobial screening service whilst retaining reliability.
  • Our scientists can help you design high-throughput protocols for your bespoke application.

Call for a friendly chat!

More Details

Toxicity

Antimicrobial Susceptibility Testing

  • Use of BSL1 and BSL2 pathogens
  • Minimum Inhibitory Concentration
  • Minimum Bactericidal Concentration
  • Minimum Biofilm Eradication Concentration
  • Checkerboard Synergy
  • Disk Diffusion
  • Time-kill
  • Post-Antimicrobial Effect
  • E-test
  • DNA/RNA extraction

Resistance

Structural biology services

  • Structural biology: X-ray crystallography, small angle X-ray scattering (SAXS), analysis of protein-ligand interactions.
  • Protein production: cloning, expression and purification.
  • Wide range of biochemical and biophysical assays for activity and binding measurements.

Pig bronchiole with bacterial biofilm

Ex Vivo Lung Biofilm Infection Model

  • 3Rs compliant
  • Respiratory pathogens
  • Bacteria / fungi (in development) / viruses (in development)
  • Specialised cystic fibrosis model available
  • Other lung conditions may be available on request
  • Detailed information

Mode of Action

Coming soon - Virology Screening

  • ISO 21702: Measurement of antiviral activity on plastics and other non-porous surfaces.
  • Various viruses available
  • Various cell lines available
  • Various molecular detection services
  • Many other virology services available.

Genomics

  • Next Generation Sequencing
  • Sanger Sequencing
  • Microarrays
  • Real time PCR

Warwick Scientific Services

  • See what else Warwick has available
  • World-class analytical support
  • Custom synthesis
  • Work bespoke to your needs

 

https://warwick.ac.uk/wss

Resistance Generation

  • Sub-MIC Selection
  • Mutation Rate Calculations
  • Resistant mutants
  • Genomic Sequencing